measure minute concentrations of NO

Unisense NO-100Nitric oxide plays an important role in many biological processes; however, natural concentrations are often in the nanomolar range. The Unisense NO microsensor is characterized by a very high sensitivity, which enables you to measure minute concentrations of NO. Combined with a fast response time the Unisense NO microsensor is an excellent research tool for a broad range of tasks.

The sensor can be used equally well for measurements in tissue, air, or liquid, and is applied in a broad variety of research fields where non-destructive, fast and accurate measurements are required. The NO microsensor is designed for research applications within:

  • Environmental sciences
  • Biomedical sciences
  • Biotechnology
  • Wastewater

Download Unisense Microsensors Brochure

 

microsensor technology

Unisense pH_brainThe NO micro- and minisensors are Clark-type sensors measuring the external NO partial pressure. The working principle of the sensor is based on diffusion of NO through a silicone membrane to an NO oxidizing anode, which is polarized against an internal counter cathode. The resulting sensor signal is in the pA range and is measured by a high quality picoammeter e.g. the Unisense Microsensor Multimeter.
Compared to other standard NO sensors the Unisense NO microsensor has an extremely low consumption of max. 935 pmol/hour corresponding to 0,1 %/hour in a 1 mL 0,1uM NO sample.

part numbers and outside tip diameter

  • PageLines-UnisenseMultimeter-FRONT.jpgNO-10: 8-12 µm
  • NO-25: 20-30 µm
  • NO-100: 90-110 µm
  • NO-500: 400-600 µm
  • NO-MR: 400-600 µm
  • NO-NP: 1.6 x 40 mm – needle sensor for piercing

 

specifications

Download NO Microsensor Spec Sheet

manual

Download NO Sensor Manual

 

references

Schreiber,F. et al (2008), Nitric Oxide Microsensor for High Spatial Resolution Measurements in Biofilms and Sediments, Anal.Chem, 1152 – 1158, vol. 80

Aamand,R. et al (2009), Generation of nitric oxide from nitrite by carbonic anhydrase: a possible link between metabolic activity and vasodilation, American Journal of Physiology- Heart and Circulatory Physiology, H2068 – , vol. 297

Ettwig,K.F. et al (2010), Nitrite-driven anaerobic methane oxidation by oxygenic bacteria, Nature, 543 – 548, vol. 464

 

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